Evaluation of the Effect of Ethanol Seed Extract of Telfairia. occidentalis on the Hepatic Health of Diabetic Rats.

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Published: Oct 22, 2022
DOI: https://doi.org/10.47191/ijpbms/v2-i10-09
Keywords:
Telieferia occidentalis, Diabetic, Aspartate transaminase, Alanine amino transaminase, Alkaline phosphatase

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Okoyomoh Kingsley
Department of Science Laboratory Technology, Federal Polytecnic Nassarawa, Niger Stete.
Elendu Melford Uche
Department of Human Physiology, Imo State University Owerri, Nigeria.
Obioha Kennedy Chinonye
Department of Pediatrics, Federal Medical Centre Owerri Imo State, Nigeria
Iheukwumere Chinedu Barry
Department of Human Physiology, College of Medicine and Health Science, Abia State University, Uturu, Nigeria

Abstract





The aim of this study was to evaluate the effect of ethanol seed extract of Telfairia. occidentalis on the activity of liver enzymes in diabetic rats. Freshly harvested seed of T. occidentalis was processed into extract. Twenty (25) adult male wistar rats were divided into five (5) groups of five rats each. Group I was fed normal rat chow and water only, Group II was diabetic; untreated rats, Groups III and IV were diabetic; treated with 150 mg/kg and 250 mg/kg extract of T. occidentalis seed. The activity of serum hepatomarkers (Aspartate transaminase, Alanine amino transaminase and Alkaline phosphatase) evaluated was significantly (P<0.05) high which was reversed in a dose dependent manner. In conclusion, it has been unveiled through this study that T. occidentalis seed extract has the potential to improve hepatic health.





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How to Cite
Kingsley, O., Uche, E. M. ., Chinonye, O. K. ., & Barry, I. C. . (2022). Evaluation of the Effect of Ethanol Seed Extract of Telfairia. occidentalis on the Hepatic Health of Diabetic Rats. International Journal of Pharmaceutical and Bio Medical Science, 2(10), 425–427. https://doi.org/10.47191/ijpbms/v2-i10-09
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Vol. 2 No. 10 (2022): Volume 02 Issue 10 October 2022
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Articles
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This work is licensed under a Creative Commons Attribution 4.0 International License.

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